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Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus

TGFβ activation and signaling have been extensively studied in experimental models of allergen-induced asthma as potential therapeutic targets during chronic or acute phases of the disease. Outcomes of experimental manipulation of TGFβ activity have been variable, in part due to use of different mod...

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Detalhes bibliográficos
Main Authors: Freimuth, Julia, Clermont, Frederic F., Huang, Xiaozhu, DeSapio, Angela, Tokuyasu, Taku A., Sheppard, Dean, Akhurst, Rosemary J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497801/
https://ncbi.nlm.nih.gov/pubmed/23064636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205374109
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