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AMINOGLYCOSIDES DECREASE GLUTATHIONE PEROXIDASE-1 ACTIVITY BY INTERFERING WITH SELENOCYSTEINE INCORPORATION
Cellular glutathione peroxidase is a key intracellular antioxidant enzyme that contains a selenocysteine residue at its active site. Selenium, a selenocysteine-incorporation sequence in the 3′- untranslated region of the glutathione peroxidase mRNA, and other translational cofactors are necessary fo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472404/ https://ncbi.nlm.nih.gov/pubmed/16354666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M511295200 |
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