AMINOGLYCOSIDES DECREASE GLUTATHIONE PEROXIDASE-1 ACTIVITY BY INTERFERING WITH SELENOCYSTEINE INCORPORATION

Cellular glutathione peroxidase is a key intracellular antioxidant enzyme that contains a selenocysteine residue at its active site. Selenium, a selenocysteine-incorporation sequence in the 3′- untranslated region of the glutathione peroxidase mRNA, and other translational cofactors are necessary fo...

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Detaylı Bibliyografya
Asıl Yazarlar: Handy, Diane E., Hang, Gaozhen, Scolaro, John, Metes, Nicole, Razaq, Nadia, Yang, Yi, Loscalzo, Joseph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472404/
https://ncbi.nlm.nih.gov/pubmed/16354666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M511295200
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