LL-37 Protects Rats against Lethal Sepsis Caused by Gram-Negative Bacteria

We investigated the efficacy of LL-37, the C-terminal part of the only cathelicidin in humans identified to date (termed human cationic antimicrobial protein), in three experimental rat models of gram-negative sepsis. Adult male Wistar rats (i) were given an intraperitoneal injection of 1 mg Escheri...

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Autors principals: Cirioni, Oscar, Giacometti, Andrea, Ghiselli, Roberto, Bergnach, Cristina, Orlando, Fiorenza, Silvestri, Carmela, Mocchegiani, Federico, Licci, Alberto, Skerlavaj, Barbara, Rocchi, Marco, Saba, Vittorio, Zanetti, Margherita, Scalise, Giorgio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472226/
https://ncbi.nlm.nih.gov/pubmed/16641434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1672-1679.2006
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