Cecropin B Enhances Betalactams Activities in Experimental Rat Models of Gram-Negative Septic Shock

OBJECTIVE: To investigate the efficacy of imipenem, piperacillin combined with cecropin B in the prevention of lethality in 2 rat models of septic shock. Main outcome measures were bacterial growth in blood and intra-abdominal fluid, endotoxin and TNF-α concentrations in plasma, and lethality. BACKG...

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Main Authors: Ghiselli, Roberto, Giacometti, Andrea, Cirioni, Oscar, Mocchegiani, Federico, Orlando, Fiorenza, D'Amato, Giuseppina, Sisti, Valerio, Scalise, Giorgio, Saba, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356219/
https://ncbi.nlm.nih.gov/pubmed/14745334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000108673.25385.03
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