Functional Characterization and Target Validation of Alternative Complex I of Plasmodium falciparum Mitochondria

This study reports on the first characterization of the alternative NADH:dehydrogenase (also known as alternative complex I or type II NADH:dehydrogenase) of the human malaria parasite Plasmodium falciparum, known as PfNDH2. PfNDH2 was shown to actively oxidize NADH in the presence of quinone electr...

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Autors principals: Biagini, Giancarlo A., Viriyavejakul, Parnpen, O'Neill, Paul M., Bray, Patrick G., Ward, Stephen A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472221/
https://ncbi.nlm.nih.gov/pubmed/16641458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1841-1851.2006
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