Mucosal Administration of CpG Oligodeoxynucleotide Elicits Strong CC and CXC Chemokine Responses in the Vagina and Serves as a Potent Th1-Tilting Adjuvant for Recombinant gD2 Protein Vaccination against Genital Herpes

Although sexually transmitted pathogens are capable of inducing pathogen-specific immune responses, vaginal administration of nonreplicating antigens elicits only weak, nondisseminating immune responses. The present study was undertaken to examine the potential of CpG-containing oligodeoxynucleotide...

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Bibliographic Details
Main Authors: Tengvall, Sara, Lundqvist, Annika, Eisenberg, Roselyn J., Cohen, Gary H., Harandi, Ali M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472142/
https://ncbi.nlm.nih.gov/pubmed/16699008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02013-05
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