Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses

Double-stranded RNA (dsRNA) longer than 30 bp is a key activator of the innate immune response against viral infections. It is widely assumed that the generation of dsRNA during genome replication is a trait shared by all viruses. However, to our knowledge, no study exists in which the production of...

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Bibliographic Details
Main Authors: Weber, Friedemann, Wagner, Valentina, Rasmussen, Simon B., Hartmann, Rune, Paludan, Søren R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472073/
https://ncbi.nlm.nih.gov/pubmed/16641297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.5059-5064.2006
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