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RNA Structural Elements Determine Frequency and Sites of Nonhomologous Recombination in an Animal Plus-Strand RNA Virus

For highly variable RNA viruses, RNA recombination significantly contributes to genetic variations which may lead to changes of virulence, adaptation to new hosts, escape from the host immune response, and emergence of new infectious agents. Using a system based on transfection of cells with synthet...

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Autori principali: Austermann-Busch, Sophia, Becher, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416315/
https://ncbi.nlm.nih.gov/pubmed/22532677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00864-12
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