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Uncoupling Store-Operated Ca(2+) Entry and Altered Ca(2+) Release from Sarcoplasmic Reticulum through Silencing of Junctophilin Genes
Junctophilin (JP) mediates the close contact between cell surface and intracellular membranes in muscle cells ensuring efficient excitation-contraction coupling. Here we demonstrate that disruption of triad junction structure formed by the transverse tubular (TT) invagination of plasma membrane and...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Biophysical Society
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1471867/ https://ncbi.nlm.nih.gov/pubmed/16565048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.076570 |
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