Muscle aging is associated with compromised Ca(2+) spark signaling and segregated intracellular Ca(2+) release

Reduced homeostatic capacity for intracellular Ca(2+) ([Ca(2+)](i)) movement may underlie the progression of sarcopenia and contractile dysfunction during muscle aging. We report two alterations to Ca(2+) homeostasis in skeletal muscle that are associated with aging. Ca(2+) sparks, which are the ele...

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Detalhes bibliográficos
Main Authors: Weisleder, Noah, Brotto, Marco, Komazaki, Shinji, Pan, Zui, Zhao, Xiaoli, Nosek, Thomas, Parness, Jerome, Takeshima, Hiroshi, Ma, Jianjie
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064307/
https://ncbi.nlm.nih.gov/pubmed/16943181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604166
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