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Muscle aging is associated with compromised Ca(2+) spark signaling and segregated intracellular Ca(2+) release
Reduced homeostatic capacity for intracellular Ca(2+) ([Ca(2+)](i)) movement may underlie the progression of sarcopenia and contractile dysfunction during muscle aging. We report two alterations to Ca(2+) homeostasis in skeletal muscle that are associated with aging. Ca(2+) sparks, which are the ele...
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| Главные авторы: | , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064307/ https://ncbi.nlm.nih.gov/pubmed/16943181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604166 |
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