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An Evolutionary Strategy for All-Atom Folding of the 60-Amino-Acid Bacterial Ribosomal Protein L20

We have investigated an evolutionary algorithm for de novo all-atom folding of the bacterial ribosomal protein L20. We report results of two simulations that converge to near-native conformations of this 60-amino-acid, four-helix protein. We observe a steady increase of “native content” in both simu...

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Hlavní autoři: Schug, A., Wenzel, W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1471866/
https://ncbi.nlm.nih.gov/pubmed/16565067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.070409
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