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Conformational Analysis of Single DNA Molecules Undergoing Entropically Induced Motion in Nanochannels

We have used the interface between a nanochannel and a microchannel as a tool for applying controlled forces on a DNA molecule. A molecule, with a radius of gyration larger than the nanochannel width, that straddles such an interface is subject to an essentially constant entropic force, which can be...

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Detalhes bibliográficos
Main Authors: Mannion, J. T., Reccius, C. H., Cross, J. D., Craighead, H. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1471858/
https://ncbi.nlm.nih.gov/pubmed/16732056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.074732
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