Recognition of GC base pairs by triplex forming oligonucleotides containing nucleosides derived from 2-aminopyridine.

We have attempted to alleviate the pH dependency of triplex recognition of guanine by using intermolecular triplexes containing 2-amino-5-(2-deoxy-d-ribofuranosyl)pyridine (AP) as an analogue of 2'-deoxycytidine (dC). We find that for the beta-anomer of AP, the complex between (AP)6T6and the target...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Cassidy, S A, Slickers, P, Trent, J O, Capaldi, D C, Roselt, P D, Reese, C B, Neidle, S, Fox, K R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147136/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9396793/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.24.4891
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