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Drosophila Costal1 mutations are alleles of protein kinase A that modulate hedgehog signaling.

Hedgehog (Hh) signaling is crucial for the development of many tissues, and altered Hh signal transduction can result in cancer. The Drosophila Costal1 (Cos1) and costal2 (cos2) genes have been implicated in Hh signaling. cos2 encodes a kinesin-related molecule, one component of a cytoplasmic comple...

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Détails bibliographiques
Auteurs principaux: Collier, Lara S, Suyama, Kaye, Anderson, Joseph H, Scott, Matthew P
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470909/
https://ncbi.nlm.nih.gov/pubmed/15238528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.024992
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