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Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction
Hedgehog (Hh) signaling is critical for many developmental events and must be restrained to prevent cancer. A transmembrane protein, Smoothened (Smo), is necessary to transcriptionally activate Hh target genes. Smo activity is blocked by the Hh transmembrane receptor Patched (Ptc). The reception of...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196058/ https://ncbi.nlm.nih.gov/pubmed/12730121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1080803 |
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