NMR determination of the conformational and drug binding properties of the DNA heptamer d(GpCpGpApApGpC) in aqueous solution.

1D and 2D NMR spectroscopy (500/600 MHz) has been used to investigate the equilibrium conformational states of the deoxyheptanucleotide 5'-d(GpCpGpApApGpC), as well as its complexation with the phenanthridinium drug ethidium bromide (EB). Quantitative determination (reaction constants and thermodyna...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Davies, D B, Pahomov, V I, Veselkov, A N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147085/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358161/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4523
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