Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.

The Rad50:Mre11:Xrs2 (RMX) complex functions in repair of DNA double-strand breaks (DSBs) by recombination and nonhomologous end-joining (NHEJ) and is also required for telomere stability. The Mre11 subunit exhibits nuclease activities in vitro, but the role of these activities in repair in mitotic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lewis, L Kevin, Storici, Francesca, Van Komen, Stephen, Calero, Shanna, Sung, Patrick, Resnick, Michael A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2004
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470833/
https://ncbi.nlm.nih.gov/pubmed/15126391
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