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Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation

Several recent findings have indicated that the promyelocytic leukemia gene product (PML) oncogenic domains (PODs) are involved in proteasome-mediated degradation of ubiquitinated proteins. We wanted to examine the intracellular distribution of PML protein in the presence of a proteasome inhibitor....

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Mattsson, Karin, Pokrovskaja, Katja, Kiss, Csaba, Klein, George, Szekely, Laszlo
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14700/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158586/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.031566998
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