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Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation

Several recent findings have indicated that the promyelocytic leukemia gene product (PML) oncogenic domains (PODs) are involved in proteasome-mediated degradation of ubiquitinated proteins. We wanted to examine the intracellular distribution of PML protein in the presence of a proteasome inhibitor....

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Detalles Bibliográficos
Main Authors: Mattsson, Karin, Pokrovskaja, Katja, Kiss, Csaba, Klein, George, Szekely, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC14700/
https://ncbi.nlm.nih.gov/pubmed/11158586
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