The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage

Apoptosis is controlled by a complex interplay between regulatory proteins. Previous work has shown that Xenopus embryos remove damaged cells by apoptosis when irradiated before, but not after, the midblastula transition (MBT). Here we demonstrate that Akt/protein kinase B is activated and mediates...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Finkielstein, Carla V., Lewellyn, Andrea L., Maller, James L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.3.1006
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