The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage

Apoptosis is controlled by a complex interplay between regulatory proteins. Previous work has shown that Xenopus embryos remove damaged cells by apoptosis when irradiated before, but not after, the midblastula transition (MBT). Here we demonstrate that Akt/protein kinase B is activated and mediates...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Finkielstein, Carla V., Lewellyn, Andrea L., Maller, James L.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2001
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.3.1006
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