Cytochromes P450 in benzene metabolism and involvement of their metabolites and reactive oxygen species in toxicity.

Cytochrome P450 (CYP) 2E1 was the most efficient CYP enzyme that oxidized benzene to soluble and covalently bound metabolites in rat and human liver microsomes. The covalent binding was due mostly to the formation of benzoquinone (BQ), the oxidation product of hydroquinone (HQ), and was inversely re...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Gut, I, Nedelcheva, V, Soucek, P, Stopka, P, Tichavská, B
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1469770/
https://ncbi.nlm.nih.gov/pubmed/9118895
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars