Mutational analysis of vaccinia virus topoisomerase identifies residues involved in DNA binding.

Vaccinia DNA topoisomerase catalyzes the cleavage and re-joining of DNA strands through a DNA-(3'-phosphotyrosyl)-enzyme intermediate formed at a specific target sequence, 5'-(C/T)CCTT downward arrow. The 314 aa protein consists of three protease-resistant structural domains demarcated by protease-s...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Sekiguchi, J, Shuman, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3649
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