Mutational analysis of vaccinia virus topoisomerase identifies residues involved in DNA binding.
Vaccinia DNA topoisomerase catalyzes the cleavage and re-joining of DNA strands through a DNA-(3'-phosphotyrosyl)-enzyme intermediate formed at a specific target sequence, 5'-(C/T)CCTT downward arrow. The 314 aa protein consists of three protease-resistant structural domains demarcated by protease-s...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3649 |
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