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Evaluation of 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) as a new sulfurizing reagent in combination with labile exocyclic amino protecting groups for solid-phase oligonucleotide synthesis.

3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) was recently introduced as an efficient sulfurizing reagent for solid-phase oligonucleotide synthesis. The successful syntheses were performed using standard base protecting groups (i.e. benzoyl for A and C, isobutyryl for G), which required deprotection in...

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Uloženo v:
Vydáno v:Nucleic Acids Res
Hlavní autoři: Ma, M Y, Dignam, J C, Fong, G W, Li, L, Gray, S H, Jacob-Samuel, B, George, S T
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3590
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