Evaluation of 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) as a new sulfurizing reagent in combination with labile exocyclic amino protecting groups for solid-phase oligonucleotide synthesis.

3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) was recently introduced as an efficient sulfurizing reagent for solid-phase oligonucleotide synthesis. The successful syntheses were performed using standard base protecting groups (i.e. benzoyl for A and C, isobutyryl for G), which required deprotection in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ma, M Y, Dignam, J C, Fong, G W, Li, L, Gray, S H, Jacob-Samuel, B, George, S T
פורמט: Artigo
שפה:Inglês
יצא לאור: 1997
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC146937/
https://ncbi.nlm.nih.gov/pubmed/9278478
תגים: הוספת תג
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