Effects of base mismatches on joining of short oligodeoxynucleotides by DNA ligases.

The requirement for Watson-Crick base pairing surrounding a nick in duplex DNA to be sealed by DNA ligase is the basis for oligonucleotide ligation assays that distinguish single base mutations in DNA targets. Experiments in a model system demonstrate that the minimum length of oligonucleotide that...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Pritchard, C E, Southern, E M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9254695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.17.3403
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