Effects of base mismatches on joining of short oligodeoxynucleotides by DNA ligases.
The requirement for Watson-Crick base pairing surrounding a nick in duplex DNA to be sealed by DNA ligase is the basis for oligonucleotide ligation assays that distinguish single base mutations in DNA targets. Experiments in a model system demonstrate that the minimum length of oligonucleotide that...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9254695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.17.3403 |
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