DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs.

We have analysed the DNA cleavage reaction of DNA gyrase using oligonucleotides annealed to a single-stranded M13 derivative containing a preferred gyrase cleavage site. We find that gyrase can cleave duplexes down to approximately 20 bp in size in the presence of the quinolone drugs ciprofloxacin a...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Cove, M E, Tingey, A P, Maxwell, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.14.2716
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