DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs.
We have analysed the DNA cleavage reaction of DNA gyrase using oligonucleotides annealed to a single-stranded M13 derivative containing a preferred gyrase cleavage site. We find that gyrase can cleave duplexes down to approximately 20 bp in size in the presence of the quinolone drugs ciprofloxacin a...
Guardat en:
| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.14.2716 |
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