DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs.

We have analysed the DNA cleavage reaction of DNA gyrase using oligonucleotides annealed to a single-stranded M13 derivative containing a preferred gyrase cleavage site. We find that gyrase can cleave duplexes down to approximately 20 bp in size in the presence of the quinolone drugs ciprofloxacin a...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Cove, M E, Tingey, A P, Maxwell, A
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 1997
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.14.2716
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