A macrocyclic bis-acridine shifts the equilibrium from duplexes towards DNA hairpins.
Nucleic acids can undergo dynamic conformational changes associated with the regulation of biological processes. A molecule presenting larger affinities for alternative structures relative to a duplex is expected to modify such conformational equilibria. We have previously reported that macrocyclic...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1997
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9185566/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.13.2574 |
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