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A macrocyclic bis-acridine shifts the equilibrium from duplexes towards DNA hairpins.

Nucleic acids can undergo dynamic conformational changes associated with the regulation of biological processes. A molecule presenting larger affinities for alternative structures relative to a duplex is expected to modify such conformational equilibria. We have previously reported that macrocyclic...

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Detalhes bibliográficos
Main Authors: Slama-Schwok, A, Peronnet, F, Hantz-Brachet, E, Taillandier, E, Teulade-Fichou, M P, Vigneron, J P, Best-Belpomme, M, Lehn, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146785/
https://ncbi.nlm.nih.gov/pubmed/9185566
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