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A macrocyclic bis-acridine shifts the equilibrium from duplexes towards DNA hairpins.

Nucleic acids can undergo dynamic conformational changes associated with the regulation of biological processes. A molecule presenting larger affinities for alternative structures relative to a duplex is expected to modify such conformational equilibria. We have previously reported that macrocyclic...

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Udgivet i:Nucleic Acids Res
Principais autores: Slama-Schwok, A, Peronnet, F, Hantz-Brachet, E, Taillandier, E, Teulade-Fichou, M P, Vigneron, J P, Best-Belpomme, M, Lehn, J M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9185566/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.13.2574
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