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Polar side chains drive the association of model transmembrane peptides

The forces stabilizing the three-dimensional structures of membrane proteins are currently not well understood. Previously, it was shown that a single Asn side chain in a transmembrane segment can mediate the dimerization and trimerization of a variety of hydrophobic helices. Here, we examine the te...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Gratkowski, Holly, Lear, James D., DeGrado, William F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2001
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14678/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158564/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.3.880
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