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The sequence specificity of alkylation for a series of benzoic acid mustard and imidazole-containing distamycin analogues: the importance of local sequence conformation.

The covalent sequence specificity of a series of nitrogen mustard and imidazole-containing analogues of distamycin was determined using modified sequencing techniques. The analogues tether benzoic acid mustard (BAM) and possess either one, two or three imidazole units. Examination of the alkylation...

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Publicat a:Nucleic Acids Res
Autors principals: Wyatt, M D, Lee, M, Hartley, J A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1997
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9171086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.12.2359
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