Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments.

Functional analysis of mammalian genes relies, in part, on targeted mutations generated by homologous recombination in mice. We have developed a strategy for adipose-specific inactivation of loxP-floxed gene segments. Transgenic mice have been established that express Cre recombinase under the contr...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Barlow, C, Schroeder, M, Lekstrom-Himes, J, Kylefjord, H, Deng, C X, Wynshaw-Boris, A, Spiegelman, B M, Xanthopoulos, K G
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146759/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9171115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.12.2543
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