Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments.

Functional analysis of mammalian genes relies, in part, on targeted mutations generated by homologous recombination in mice. We have developed a strategy for adipose-specific inactivation of loxP-floxed gene segments. Transgenic mice have been established that express Cre recombinase under the contr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Barlow, C, Schroeder, M, Lekstrom-Himes, J, Kylefjord, H, Deng, C X, Wynshaw-Boris, A, Spiegelman, B M, Xanthopoulos, K G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC146759/
https://ncbi.nlm.nih.gov/pubmed/9171115
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