Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA.

We have tested the inhibitory potential of peptide nucleic acid (PNA) on in vitro reverse transcription of the HIV-1 gag gene. PNA was designed to target different regions of the HIV-1 gag gene and the effect on reverse transcription by HIV-1, MMLV and AMV reverse transcriptases (RTs) was investigat...

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Bibliografski detalji
Glavni autori: Koppelhus, U, Zachar, V, Nielsen, P E, Liu, X, Eugen-Olsen, J, Ebbesen, P
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC146729/
https://ncbi.nlm.nih.gov/pubmed/9153317
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