Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA.

We have tested the inhibitory potential of peptide nucleic acid (PNA) on in vitro reverse transcription of the HIV-1 gag gene. PNA was designed to target different regions of the HIV-1 gag gene and the effect on reverse transcription by HIV-1, MMLV and AMV reverse transcriptases (RTs) was investigat...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Koppelhus, U, Zachar, V, Nielsen, P E, Liu, X, Eugen-Olsen, J, Ebbesen, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146729/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9153317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.11.2167
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