Processive proofreading by the adenovirus DNA polymerase. Association with the priming protein reduces exonucleolytic degradation.

By using a baculovirus expression system, the adenovirus (Ad) DNA polymerase was purified to homogeneity and shown to display a 3'-->5'exonuclease activity which is coupled to the polymerase activity. On a partial duplex structure the exonuclease activity had a marked preference for excision of a mi...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	King, A J, Teertstra, W R, Blanco, L, Salas, M, van der Vliet, P C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.9.1745
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