Cre-mediated somatic site-specific recombination in mice.

Conditional mutant mice equipped with heterologous recombination systems (Cre/lox or Flp/frt) are promising for studying tissue-specific gene function and for designing better models of human diseases. The utility of these mice depends on the cell target specificity, on the efficiency and on the con...

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Main Authors: Akagi, K, Sandig, V, Vooijs, M, Van der Valk, M, Giovannini, M, Strauss, M, Berns, A
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC146656/
https://ncbi.nlm.nih.gov/pubmed/9108159
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