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B lymphocyte-specific, Cre-mediated mutagenesis in mice.

Adaptation of the P1 phage-derived Cre /loxP site- specific recombination system to the gene targeting technique allows for the conditional deletion of genes in mice. To selectively modify genes in B lymphocytes, we have generated mice (designated CD19-Cre) which express cre under the transcriptiona...

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Sonraí Bibleagrafaíochta
Main Authors: Rickert, R C, Roes, J, Rajewsky, K
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1997
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC146582/
https://ncbi.nlm.nih.gov/pubmed/9092650
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