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Permanent hapten-specific tolerance in B lymphocytes.

Tolerance to the hapten TNP was induced in mice congenic with CBA but bearing the Ig-b allotype (Ig-b mice). To induce a high degree of tolerance it was necessary to give five injections of TNP-sulphonate followed by an immunogenic challenge (alum precipitate of TNP-BSA with pertussis adjuvant). Lym...

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Dettagli Bibliografici
Autori principali: Elson, C J, Taylor, R B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1975
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1445773/
https://ncbi.nlm.nih.gov/pubmed/1079199
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