Substrate and mispairing properties of 5-formyl-2'-deoxyuridine 5'-triphosphate assessed by in vitro DNA polymerase reactions.

5-Formyluracil (fU) is one of the thymine lesions produced by reactive oxygen radicals in DNA and its constituents. In this work, 5-formyl-2'-deoxyuridine 5'-triphosphate (fdUTP) was chemically synthesized and extensively purified by HPLC. The electron withdrawing 5-formyl group facilitated ionizati...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Yoshida, M, Makino, K, Morita, H, Terato, H, Ohyama, Y, Ide, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9092664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.8.1570
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