Substrate and mispairing properties of 5-formyl-2'-deoxyuridine 5'-triphosphate assessed by in vitro DNA polymerase reactions.

5-Formyluracil (fU) is one of the thymine lesions produced by reactive oxygen radicals in DNA and its constituents. In this work, 5-formyl-2'-deoxyuridine 5'-triphosphate (fdUTP) was chemically synthesized and extensively purified by HPLC. The electron withdrawing 5-formyl group facilitate...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yoshida, M, Makino, K, Morita, H, Terato, H, Ohyama, Y, Ide, H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC146632/
https://ncbi.nlm.nih.gov/pubmed/9092664
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk