Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites.

The mutagenic and lethal effects of abasic sites in DNA are averted by repair initiated by 'class II' apurinic (AP) endonucleases, which cleave immediately 5'to abasic sites. We examined substrate binding by the human AP endonuclease, Ape protein (also called Hap1, Apex or Ref-1). In electrophoretic...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Wilson, D M, Takeshita, M, Demple, B
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.5.933
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