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Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites.

The mutagenic and lethal effects of abasic sites in DNA are averted by repair initiated by 'class II' apurinic (AP) endonucleases, which cleave immediately 5'to abasic sites. We examined substrate binding by the human AP endonuclease, Ape protein (also called Hap1, Apex or Ref-1). In electrophoretic...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Wilson, D M, Takeshita, M, Demple, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 1997
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146540/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023101/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.5.933
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