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Paradoxical SR Ca(2+) release in guinea-pig cardiac myocytes after β-adrenergic stimulation revealed by two-photon photolysis of caged Ca(2+)

In heart muscle the amplification and shaping of Ca(2+) signals governing contraction are orchestrated by recruiting a variable number of Ca(2+) sparks. Sparks reflect Ca(2+) release from the sarcoplasmic reticulum (SR) via Ca(2+) release channels (ryanodine receptors, RyRs). RyRs are activated by C...

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Hlavní autoři: Lindegger, Nicolas, Niggli, Ernst
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464544/
https://ncbi.nlm.nih.gov/pubmed/15774509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.084376
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