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Paradoxical block of the Na(+)-Ca(2+) exchanger by extracellular protons in guinea-pig ventricular myocytes

1. The Na(+)-Ca(2+) exchange is a major pathway for removal of cytosolic Ca(2+) in cardiac myocytes. It is known to be inhibited by changes of intracellular pH that may occur, for example, during ischaemia. In the present study, we examined whether extracellular protons (pH(o)) can also affect the c...

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Detalhes bibliográficos
Main Authors: Egger, Marcel, Niggli, Ernst
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269805/
https://ncbi.nlm.nih.gov/pubmed/10699080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-1-00353.x
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